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1

Geschichte der Antike ||

Funke, Peter, Herz, Peter, Hölkeskamp, Karl-Joachim, Krause, Jens-Uwe, Stein-Hölkeskamp, Elke, Wiesehöfer, Josef, Gehrke, Hans-Joachim, Schneider, Helmuth

Année:

2013

Langue:

german

Fichier:

PDF, 18.28 MB

german, 2013

2

Geschichte der Antike ||

Gehrke, Hans-Joachim, Schneider, Helmuth, Funke, Peter, Herz, Peter, Hölkeskamp, Karl-Joachim, Krause, Jens-Uwe, Stein-Hölkeskamp, Elke, Wiesehöfer, Josef

Année:

2013

Langue:

german

Fichier:

PDF, 3.51 MB

german, 2013

3

Aminomethylpyrimidines as Novel DPP-IV Inhibitors: A 105-Fold Activity Increase by Optimization of Aromatic Substituents.

Jens-Uwe Peters, Silja Weber, Stephane Kritter, Peter Weiss, Angelina Wallier, Markus Boehringer, Michael Hennig, Bernd Kuhn, Bernd-Michael Loeffler

Journal:

Année:

2004

Fichier:

PDF, 90 KB

2004

4

Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands

Jens-Uwe Peters, Torsten Hoffmann, Patrick Schnider, Heinz Stadler, Andreas Koblet, André Alker, Sonia Maria Poli, Theresa M. Ballard, Will Spooren, Lucinda Steward, Andrew J. Sleight

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2010

5

Polypharmacology in Drug Discovery (Peters/Polypharmacology) || Pharmacological Promiscuity and Molecular Properties

Peters, Jens-Uwe

Année:

2012

Langue:

english

Fichier:

PDF, 304 KB

english, 2012

6

Polypharmacology – Foe or Friend?

Peters, Jens-Uwe

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2013

7

How to Define End-Diastole and End-Systole?

Mada, Razvan O., Lysyansky, Peter, Daraban, Ana M., Duchenne, Jürgen, Voigt, Jens-Uwe

Journal:

Journal of the American College of Cardiology: Cardiovascular Imaging

Année:

2015

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2015

8

Incidence of Histologically Proven Pelvic and Para-Aortic Lymph Node Metastases and Rate of Upstaging in Patients with Locally Advanced Cervical Cancer: Results of a Prospective Randomized Trial

Tsunoda, Audrey Tieko, Marnitz, Simone, Soares Nunes, Joao, Mattos de Cunha Andrade, Carlos Eduardo, Scapulatempo Neto, Christovam, Blohmer, Jens-Uwe, Herrmann, Jörg, Kerr, Ligia Maria, Martus, Peter,

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 88 KB

english, 2017

9

Safety screening in early drug discovery: An optimized assay panel

Bendels, Stefanie, Bissantz, Caterina, Fasching, Bernhard, Gerebtzoff, Grégori, Guba, Wolfgang, Kansy, Manfred, Migeon, Jacques, Mohr, Susanne, Peters, Jens-Uwe, Tillier, Fabien, Wyler, René, Lerner,

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2019

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2019

10

Iminium Ion Catalysis: Use of the α-Effect in the Acceleration of the Diels—Alder Reaction

Julie L. Cavill, Jens-Uwe Peters, Nicholas C. O. Tomkinson

Journal:

Année:

2003

Fichier:

PDF, 89 KB

2003

11

An Aminomethylpyrimidine DPP-IV Inhibitor with Improved Properties.

Jens-Uwe Peters, et al. et al.

Journal:

Année:

2004

Fichier:

PDF, 21 KB

2004

12

Aminomethylpyridines as DPP-IV Inhibitors.

Jens-Uwe Peters, Silja Weber, Stephane Kritter, Peter Weiss, Angelina Wallier, Daniel Zimmerli, Markus Boehringer, Matthias Steger, Bernd-Michael Loeffler

Journal:

Année:

2004

Fichier:

PDF, 16 KB

2004

13

Mizellare Extraktion von Zink mit Di(2-ethylhexyl)phosphorsäure in Gegenwart des Tensids Cetyltrimethylammoniumbromid

Dr. Simone Raatz, Dr. Peter Klapper, Prof. Jens-Uwe Repke

Journal:

Chemie Ingenieur Technik

Année:

2011

Langue:

german

Fichier:

PDF, 236 KB

german, 2011

14

Metabolite Identification via LC-SPE-NMR-MS of the In vitro Biooxidation Products of a Lead mGlu5 Allosteric Antagonist and Impact on the Improvement of Metabolic Stability in the Series

Simona M. Ceccarelli, Götz Schlotterbeck, Patrick Boissin, Martin Binder, Bernd Buettelmann, Steven Hanlon, Georg Jaeschke, Sabine Kolczewski, Ernst Kupfer, Jens-Uwe Peters, Richard H. P. Porter, Eric

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 448 KB

english, 2008

15

Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds

Jens-Uwe Peters, Patrick Schnider, Patrizio Mattei, Manfred Kansy

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 586 KB

english, 2009

16

7-hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors

Diego J. Walther, Jens-Uwe Peter, Michael Bader

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 154 KB

english, 2002

17

Synthesis of [3H]fenobam, a radioligand for the mGlu5 receptor

Thomas Hartung, Jens-Uwe Peters, Jürgen Wichmann, Christian Hubschwerlen, Georg Jaeschke

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2008

Langue:

english

Fichier:

PDF, 102 KB

english, 2008

18

Using databases to support the development of microcode

Jens-Uwe Dzikowski, Peter A Rounce

Journal:

Microprocessors and Microsystems

Année:

1994

Langue:

english

Fichier:

PDF, 918 KB

english, 1994

19

Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Optimising brain penetration

Jens-Uwe Peters, Thomas Lübbers, Alexander Alanine, Sabine Kolczewski, Francesca Blasco, Lucinda Steward

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 189 KB

english, 2008

20

Aminomethylpyrimidines as novel DPP-IV inhibitors: A 105-fold activity increase by optimization of aromatic substituents

Jens-Uwe Peters, Silja Weber, Stéphane Kritter, Peter Weiss, Angelina Wallier, Markus Boehringer, Michael Hennig, Bernd Kuhn, Bernd-Michael Loeffler

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 179 KB

english, 2004

21

Aminomethylpyridines as DPP-IV inhibitors

Jens-Uwe Peters, Silja Weber, Stéphane Kritter, Peter Weiss, Angelina Wallier, Daniel Zimmerli, Markus Boehringer, Matthias Steger, Bernd-Michael Loeffler

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 241 KB

english, 2004

22

Arylmethoxypyridines as novel, potent and orally active mGlu5 receptor antagonists

Bernd Büttelmann, Jens-Uwe Peters, Simona Ceccarelli, Sabine Kolczewski, Eric Vieira, Eric P. Prinssen, Will Spooren, Franz Schuler, Jörg Huwyler, Richard H.P. Porter, Georg Jaeschke

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 170 KB

english, 2006

23

Rational design, synthesis, and structure–activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure

Simona M. Ceccarelli, Georg Jaeschke, Bernd Buettelmann, Jörg Huwyler, Sabine Kolczewski, Jens-Uwe Peters, Eric Prinssen, Richard Porter, Will Spooren, Eric Vieira

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 172 KB

english, 2007

24

1,3-Disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors

Thomas Lübbers, Markus Böhringer, Luca Gobbi, Michael Hennig, Daniel Hunziker, Bernd Kuhn, Bernd Löffler, Patrizio Mattei, Robert Narquizian, Jens-Uwe Peters, Yves Ruff, Hans Peter Wessel, Pierre Wyss

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 420 KB

english, 2007

25

Novel orally active, dibenzazepinone-based γ-secretase inhibitors

Jens-Uwe Peters, Guido Galley, Helmut Jacobsen, Christian Czech, Pascale David-Pierson, Eric A. Kitas, Laurence Ozmen

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 164 KB

english, 2007

26

Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Structure–activity relationship elucidation

Jens-Uwe Peters, Thomas Lübbers, Alexander Alanine, Sabine Kolczewski, Francesca Blasco, Lucinda Steward

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 155 KB

english, 2008

27

Tyramine fragment binding to BACE-1

Andreas Kuglstatter, Martin Stahl, Jens-Uwe Peters, Walter Huber, Martine Stihle, Daniel Schlatter, Jörg Benz, Armin Ruf, Doris Roth, Thilo Enderle, Michael Hennig

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 731 KB

english, 2008

28

Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: Optimization of in vitro activity

Jens-Uwe Peters, Holger Kühne, Henrietta Dehmlow, Uwe Grether, Aurelia Conte, Dominik Hainzl, Cornelia Hertel, Nicole A. Kratochwil, Michael Otteneder, Robert Narquizian, Constantinos G. Panousis, Fab

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 678 KB

english, 2010

29

A facile Horner–Wadsworth–Emmons route to 2-quinolones

Jens-Uwe Peters, Tony Capuano, Silja Weber, Stéphane Kritter, Matthias Sägesser

Journal:

Tetrahedron Letters

Année:

2008

Langue:

english

Fichier:

PDF, 113 KB

english, 2008

30

Synthesis of potential drug metabolites by a modified Udenfriend reaction

Roger Slavik, Jens-Uwe Peters, Rudolf Giger, Markus Bürkler, Eric Bald

Journal:

Tetrahedron Letters

Année:

2011

Langue:

english

Fichier:

PDF, 217 KB

english, 2011

31

Multizentrische Erfahrungen mit der Stapler-Hämorrhoidenoperation

Alexander Herold, Jens J. Kirsch, Günther Staude, Thorolf Hager, Franz Raulf, Jens Michel, Jens-Uwe Bock, Jan Jongen, Peter Prohm, Norbert Wolf, Heinrich Müller-Lobeck, Klaus Gellert

Journal:

Année:

2001

Fichier:

PDF, 100 KB

2001

32

Standards and perspectives in locoregional hyperthermia

Bert Hildebrandt, Beate Rau, Johanna Gellermann, Thoralf Kerner, Annett Nicolaou, Jens-Uwe Blohmer, Ralf Ulrich Trappe, Hanno Riess, Peter Wust

Journal:

Wiener Medizinische Wochenschrift

Année:

2004

Fichier:

PDF, 261 KB

2004

33

Impact of treatment characteristics on response of different breast cancer phenotypes: pooled analysis of the German neo-adjuvant chemotherapy trials

Gunter von Minckwitz, Michael Untch, Eveline Nüesch, Sibylle Loibl, Manfred Kaufmann, Sherko Kümmel, Peter A. Fasching, Wolfgang Eiermann, Jens-Uwe Blohmer, Serban Dan Costa, Keyur Mehta, Jörn Hilfric

Journal:

Breast Cancer Research and Treatment

Année:

2011

Langue:

english

Fichier:

PDF, 330 KB

english, 2011

34

Development of antithrombotic miniribozymes that target peripheral tryptophan hydroxylase

Jens-Uwe Peter, Natalia Alenina, Michael Bader, Diego J. Walther

Journal:

Molecular and Cellular Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 373 KB

english, 2007

35

An aminomethylpyrimidine DPP-IV inhibitor with improved properties

Jens-Uwe Peters, Daniel Hunziker, Holger Fischer, Manfred Kansy, Silja Weber, Stéphane Kritter, Aranka Müller, Angelina Wallier, Fabienne Ricklin, Markus Boehringer, Sonia Maria Poli, Miklos Csato, Be

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 262 KB

english, 2004

36

Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists

Georg Jaeschke, Richard Porter, Bernd Büttelmann, Simona M. Ceccarelli, Wolfgang Guba, Bernd Kuhn, Sabine Kolczewski, Jörg Huwyler, Vincent Mutel, Jens-Uwe Peters, Theresa Ballard, Eric Prinssen, Eric

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 206 KB

english, 2007

37

Dose-dense adjuvant chemotherapy for node-positive breast cancer in women 60 years and older: Feasibility and tolerability in a subset of patients in a randomized trial

Sherko Kümmel, Jutta Krocker, Andreas Kohls, Georg-Peter Breitbach, Günther Morack, Marek Budner, Jens-Uwe Blohmer, Werner Lichtenegger, Dirk Elling

Journal:

Critical Reviews in Oncology/Hematology

Année:

2006

Langue:

english

Fichier:

PDF, 227 KB

english, 2006

38

Effects of UVB Irradiation and Diclofenac on F2-Isoprostane/Prostaglandin Concentrations in Keratinocytes and Microdialysates of Human Skin

Wiswedel, Ingrid, Grundmann, Jens-Uwe, Boschmann, Michael, Krautheim, Andrea, Böckelmann, Raik, Peter, Daniela S, Holzapfel, Imke, Götz, Stephan, Müller-Goymann, Christel, Bonnekoh, Bernd, Gollnick, H

Journal:

The Journal of Investigative Dermatology

Année:

2007

Langue:

english

Fichier:

PDF, 103 KB

english, 2007

39

Iminium ion catalysis: Use of the α-effect in the acceleration of the Diels–Alder reactionElectronic supplementary information (ESI) available: 1H NMR, 13C NMR, IR and MS spectra. See http://www.rsc.org/suppdata/cc/b2/b212239a/

Cavill, Julie L., Peters, Jens-Uwe, Tomkinson, Nicholas C. O.

Journal:

Chemical Communications

Année:

2003

Langue:

english

Fichier:

PDF, 94 KB

english, 2003

40

Can we discover pharmacological promiscuity early in the drug discovery process?

Jens-Uwe Peters, Jérôme Hert, Caterina Bissantz, Alexander Hillebrecht, Grégori Gerebtzoff, Stefanie Bendels, Fabien Tillier, Jacques Migeon, Holger Fischer, Wolfgang Guba, Manfred Kansy

Journal:

Drug Discovery Today

Année:

2012

Langue:

english

Fichier:

PDF, 633 KB

english, 2012

41

Efficacy and Safety of TachoSil® as Haemostatic Treatment versus Standard Suturing in Kidney Tumour Resection: A Randomised Prospective Study

Stefan Siemer, Sven Lahme, Stefan Altziebler, Stefan Machtens, Walter Strohmaier, Hans-W. Wechsel, Peter Goebell, Nicolaus Schmeller, Ralph Oberneder, Jens-Uwe Stolzenburg, Hermann Becker, Werner Lüft

Journal:

European Urology

Année:

2007

Langue:

english

Fichier:

PDF, 239 KB

english, 2007

42

FTMW and millimeter wave spectroscopy of benzanthrone

Don McNaughton, Peter D. Godfrey, Jens-Uwe Grabow

Journal:

Journal of Molecular Spectroscopy

Année:

2012

Langue:

english

Fichier:

PDF, 249 KB

english, 2012

43

Influence of constraints and twinning stress on magnetic field-induced strain of magnetic shape-memory alloys

Markus Chmielus, Illya Glavatskyy, Jens-Uwe Hoffmann, Volodymyr A. Chernenko, Rainer Schneider, Peter Müllner

Journal:

Scripta Materialia

Année:

2011

Langue:

english

Fichier:

PDF, 392 KB

english, 2011

44

Impact of aircraft emissions on tropospheric and stratospheric ozone. Part I: chemistry and 2-D model results

Jens-uwe Grooß, Christoph Brühl, Thomas Peter

Journal:

Atmospheric Environment

Année:

1998

Langue:

english

Fichier:

PDF, 317 KB

english, 1998

45

Designing Multi-Target Drugs Edited by J. Richard Morphy and C. John Harris.

Dr. Jens-Uwe Peters

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 195 KB

english, 2012

46

Serotonylation of Small GTPases Is a Signal Transduction Pathway that Triggers Platelet α-Granule Release

Diego J Walther, Jens-Uwe Peter, Sandra Winter, Markus Höltje, Nils Paulmann, Maik Grohmann, Jakob Vowinckel, Victor Alamo-Bethencourt, Claudia S Wilhelm, Gudrun Ahnert-Hilger, Michael Bader

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 642 KB

english, 2003

47

Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial

Michael Untch, Sibylle Loibl, Joachim Bischoff, Holger Eidtmann, Manfred Kaufmann, Jens-Uwe Blohmer, Jörn Hilfrich, Dirk Strumberg, Peter A Fasching, Rolf Kreienberg, Hans Tesch, Claus Hanusch, Bernd

Journal:

The Lancet Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 264 KB

english, 2012

48

Occupational exposure to polycyclic aromatic hydrocarbons and DNA damage by industry: a nationwide study in Germany

Boleslaw Marczynski, Beate Pesch, Michael Wilhelm, Bernd Rossbach, Ralf Preuss, Jens-Uwe Hahn, Sylvia Rabstein, Monika Raulf-Heimsoth, Albrecht Seidel, Hans-Peter Rihs, Ansgar Adams, Michael Scherenbe

Journal:

Archives of Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 403 KB

english, 2009

49

Systematic Review and Meta-analysis of Studies Reporting Urinary Continence Recovery After Robot-assisted Radical Prostatectomy

Vincenzo Ficarra, Giacomo Novara, Raymond C. Rosen, Walter Artibani, Peter R. Carroll, Anthony Costello, Mani Menon, Francesco Montorsi, Vipul R. Patel, Jens-Uwe Stolzenburg, Henk Van der Poel, Timoth

Journal:

European Urology

Année:

2012

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2012

50

Open-label study of omega interferon in previously untreated HCV-infected patients

Mathias Mathias Plauth, Helga Meisel, Peter Langecker, Mark Moran, William Lang, Dennis Blanchett, Jens-Uwe Jetschmann, Jochen Brack, Pieter von Wussow

Journal:

Journal of Hepatology

Année:

2002

Langue:

english

Fichier:

PDF, 109 KB

english, 2002